Overview

The Role: Moderna offers the opportunity to be part of a pioneering team revolutionizing medicine through mRNA technology with a diverse pipeline across various diseases. You will be part of a growing organization, working with colleagues and strategic partners worldwide to contribute to global health initiatives. Moderna is advancing the technological frontier of mRNA medicines, offering a challenging and rewarding career with potential to impact patients globally.

Moderna's mission includes establishing a leading-edge research, development, and manufacturing facility at Harwell, UK, to onshore mRNA vaccine production for respiratory diseases. This initiative will create skilled jobs and foster collaboration with academic, NHS and government partners across the UK. We are seeking global experts eager to join this endeavour and help make life-saving vaccines accessible for all.

We are seeking a hands-on and technically adept GxP IT Systems Engineer to support Moderna’s manufacturing operations at our Harwell site. This role is highly interactive and embedded in site operations, working with automation engineers, QC analysts, warehouse teams, and manufacturing operators. You will be the critical link between IT and Operational Technology (OT), delivering robust, compliant systems performance and end-user support.

This is a dynamic opportunity for an individual contributor who thrives in complex, regulated environments and maintains the technical backbone that drives GMP production. You will gain exposure to modern observability, cybersecurity tooling, and potential collaboration with Generative AI and automation systems, placing you at the forefront of digital manufacturing in biotechnology.

What You’ll Do

Your key responsibilities will be:

• Ensure compliance with GMP and data integrity standards, supporting inspections, audits, deviations, CAPAs, and SOP adherence.
• Provide Tier 1 support for manufacturing operations, responding to shop floor issues across workstations, HMIs, scanners, label printers, and Thin Clients.
• Triage and resolve IT incidents, requests, and change controls using a service-oriented mindset and SLAs.
• Manage infrastructure operations including troubleshooting of Windows servers, VMs (VMware/Hyper-V), Active Directory, DNS/DHCP, and time sync services.
• Support change execution activities in a validated GxP environment, maintaining audit trails and system states.
• Use observability tools such as Dynatrace, Splunk, and PagerDuty to monitor system health and resolve performance issues.
• Participate in endpoint protection and vulnerability management in coordination with security teams using tools like CrowdStrike.
• Maintain CMDB accuracy, system inventories, configuration baselines, and network documentation.

Your responsibilities will also include:

• Provide day-to-day end-user IT support, including configuration and maintenance of laptops, mobile devices, and peripherals.
• Diagnose and resolve issues related to OS, Microsoft Office Suite, Outlook, and third-party applications.
• Maintain detailed documentation for tickets, repairs, imaging, data wiping, and asset tracking.
• Deliver a high-quality, customer-centric experience in all end-user interactions.
• Collaborate with QA, QC, Automation, Plant and Lab Engineering, and Digital Core teams to coordinate system downtime, restoration, and change advisory reviews.
• Participate in after-hours or weekend support activities as needed based on manufacturing demands.

The Moderna Mindsets

• We behave like owners. The solutions we’re building go beyond any job description. In this role, taking ownership is vital — you’ll be the bridge between IT, automation, and the GMP shop floor, managing essential systems that directly impact product delivery. Your ability to act proactively and think holistically ensures production continuity and regulatory alignment.
• We digitize everywhere possible using the power of code to maximize our impact on patients. As a GxP IT Systems Engineer, you’ll operate in a highly digitized environment using advanced monitoring, cybersecurity, and infrastructure automation tools. Your contribution will enable faster, smarter, and safer operations that ultimately accelerate the delivery of mRNA medicines to patients.

Qualifications and Experience

• Bachelor's degree in computer science, Information Technology, Industrial Engineering, physical science or related field or relevant experience.
• Minimum of 3-5 years of experience supporting IT/OT systems in manufacturing and labs.
• Experience working in a BioPharma, GxP environment.
• Some experience with virtual environments (VMware/Hyper-V) and/or cloud platforms (AWS preferred).
• Some experience with RDBMS (SQL Server or Oracle).
• Some experience with backup/recovery systems (Acronis, Veeam, N2WS, etc.).
• Some experience with cybersecurity endpoint protection applications (CrowdStrike, Symantec, McAfee, Carbon Black, etc.).
• Some experience with infrastructure tools (Dynatrace, PagerDuty, Splunk).
• Excellent Windows and Microsoft Office Suite troubleshooting skills, and hardware troubleshooting skills.
• Experience with Apple device support for macOS and iOS, including the JAMF environment.
• Experience with Service Now is a plus.
• Basic understanding of network routing, switching and firewall concepts.

Skills and Competencies

• Creative, analytical, and strong problem-solving skills.
• Ability to troubleshoot complex issues in a high-pressure environment.
• Ability to react under pressure in a multi-location, 24x7 environment.
• Ability to drive change in a dynamic, high-standards environment with a positive approach.
• Highly collaborative work style with strong interpersonal skills and ability to work cross-functionally in a fast-paced project environment.

Benefits and Culture

Moderna offers benefits designed to support well-being, including quality healthcare and insurance, Lifestyle Spending Accounts, fitness and mindfulness resources, family planning and adoption benefits, generous paid time off, and location-specific perks. Benefits vary by country and employment type.

About Moderna

Since 2010, Moderna has aspired to build the leading mRNA technology platform and a world-class team. We are committed to creating a culture of belonging and delivering medicines that improve patients’ lives. Moderna has been recognized by Science Magazine, Fast Company, and Great Place to Work. We advocate an in-person culture with a 70/30 in-office model to foster collaboration and mentorship.

If you want to make a difference and join a team changing the future of medicine, visit modernatx.com/careers to learn about current opportunities.

Moderna is a smoke-free, alcohol-free, and drug-free work environment.

Moderna is an equal opportunity employer. We welcome applicants regardless of race, color, sex, gender identity, age, religion, national origin, disability, or other protected characteristics, and we comply with applicable laws regarding criminal histories where required. Moderna is committed to providing reasonable accommodation during the hiring process and for employees with disabilities. For accommodations, contact leavesandaccommodations@modernatx.com.